HU-210


SMILES CCCCCCC(c1cc(O)c2c(c1)OC([C@H]1[C@H]2CC(=CC1)CO)(C)C)(C)C
InChIKey SSQJFGMEZBFMNV-WOJBJXKFSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 7
Molecular weight (Da) 386.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Structure pdb 9ERX

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB2 CNR2 Mouse Cannabinoid A pKi 9.7 9.7 9.7 ChEMBL
CB2 CNR2 Human Cannabinoid A pKi 7.75 9.07 9.82 ChEMBL
CB1 CNR1 Human Cannabinoid A pKi 7.73 8.89 10.22 ChEMBL
CB1 CNR1 Human Cannabinoid A pKi 9.1 9.65 10.2 Guide to Pharmacology
CB2 CNR2 Human Cannabinoid A pKi 9.3 9.55 9.8 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB2 CNR2 Human Cannabinoid A pEC50 8.39 8.65 9.2 ChEMBL
CB1 CNR1 Human Cannabinoid A pEC50 7.4 8.31 9.22 ChEMBL
GPR55 GPR55 Human GPR18, GPR55 and GPR119 A pEC50 7.59 7.59 7.59 Guide to Pharmacology