CHEMBL563949


SMILES Cc1c(CC(=O)O)c2cccnc2n1S(=O)(=O)c1ccc(F)c(F)c1
InChIKey HLSYGDSWXJGENX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 366.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
DP2 PD2R2 Mouse Prostanoid A pKi 7.55 7.55 7.55 ChEMBL
DP2 PD2R2 Human Prostanoid A pKi 7.48 7.5 7.51 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
DP2 PD2R2 Mouse Prostanoid A pIC50 6.78 6.78 6.78 ChEMBL
CCK1 CCKAR Human Cholecystokinin A pIC50 5.09 5.09 5.09 ChEMBL
DP2 PD2R2 Human Prostanoid A pIC50 6.82 7.52 8.05 ChEMBL