ibutamoren


SMILES O=C([C@H](NC(=O)C(N)(C)C)COCc1ccccc1)N1CCC2(CC1)CN(c1c2cccc1)S(=O)(=O)C
InChIKey UMUPQWIGCOZEOY-JOCHJYFZSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 8
Molecular weight (Da) 528.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Structure pdb 7NA8

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
ghrelin GHSR Human Ghrelin A pKi 9.62 9.62 9.62 ChEMBL
ghrelin GHSR Human Ghrelin A pKd 9.85 9.85 9.85 ChEMBL
ghrelin GHSR Human Ghrelin A pKi 9.34 9.34 9.34 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
ghrelin GHSR Rat Ghrelin A pEC50 8.89 8.89 8.89 ChEMBL
GHRH GHRHR Rat Glucagon B1 pEC50 8.82 8.82 8.82 ChEMBL
ghrelin GHSR Human Ghrelin A pIC50 6.52 8.55 9.4 ChEMBL
ghrelin GHSR Human Ghrelin A pEC50 8.85 9.19 9.7 ChEMBL
ghrelin GHSR Human Ghrelin A pEC50 8.62 9.17 9.72 Guide to Pharmacology