CHEMBL572867


SMILES COc1ccc(-n2cc(CCCC(=O)NCCCCN3CCN(c4cccc(Cl)c4Cl)CC3)nn2)cc1
InChIKey POZXHKGYVSZVAB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 12
Molecular weight (Da) 544.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Pig Dopamine A pKi 6.85 6.85 6.85 ChEMBL
D4 DRD4 Human Dopamine A pKi 5.75 5.75 5.75 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.08 7.08 7.08 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.17 8.09 9.0 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database