A331440


SMILES N#Cc1ccc(cc1)c1ccc(cc1)OCCCN1CC[C@H](C1)N(C)C
InChIKey FXIPXWLVYIHFEP-OAQYLSRUSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 349.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Human Histamine A pKi 8.5 8.5 8.5 Guide to Pharmacology
H1 HRH1 Human Histamine A pKi 5.72 5.72 5.72 ChEMBL
H2 HRH2 Human Histamine A pKi 5.0 5.0 5.0 ChEMBL
H3 HRH3 Human Histamine A pKi 8.4 8.55 8.7 ChEMBL
H3 HRH3 Rat Histamine A pKi 7.87 7.87 7.87 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database