CHEMBL573791


SMILES COc1ccccc1N1CCN(CCNC(=O)c2cn(-c3ccc([N+](=O)[O-])cc3)nn2)CC1
InChIKey JIMZYWHOJZKVBJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 9
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 451.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Pig Dopamine A pKi 5.39 5.39 5.39 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.33 7.33 7.33 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.31 8.31 8.31 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.55 7.37 8.19 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database