CHEMBL575508


SMILES CC(C)[C@@H](CN1CC[C@@](C)(c2cccc(O)c2)[C@@H](C)C1)NC(=O)[C@H]1Cc2ccc(O)cc2CN1C
InChIKey OHIFKDNMHSXJFA-XAOJMSMDSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 6
Molecular weight (Da) 479.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Guinea pig Opioid A pKi 10.28 10.28 10.28 ChEMBL
μ OPRM Rat Opioid A pKi 7.43 7.43 7.43 ChEMBL
δ OPRD Human Opioid A pKi 6.93 6.93 6.93 ChEMBL
κ OPRK Human Opioid A pKi 9.0 9.41 9.81 ChEMBL
μ OPRM Human Opioid A pKi 7.51 7.78 8.05 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database