CHEMBL590078


SMILES Cc1cccc2c1C(=O)NC1CNCCN21
InChIKey RGCZEETYNQZRTH-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 0
Molecular weight (Da) 217.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.69 7.38 8.07 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.68 6.37 7.05 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.35 5.99 6.64 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 6.0 6.67 7.35 ChEMBL