CHEMBL593196


SMILES Cn1c(CN2CCC(c3ccccc3)CC2)nc2ccccc21
InChIKey JSJOIAGWCLDVRP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 305.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 7.0 7.0 7.0 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.9 6.9 6.9 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.6 7.6 7.6 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu2 GRM2 Rat Metabotropic glutamate C pEC50 6.67 6.67 6.67 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pEC50 5.2 5.95 6.7 ChEMBL