CHEMBL604897


SMILES O=C(O)/C=C/c1ccc(CN2CCCC2=O)cc1OCCc1ccc2ccccc2c1
InChIKey UZFYCISOWWEDLU-VAWYXSNFSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 415.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP1 PE2R1 Mouse Prostanoid A pKi 5.19 5.19 5.19 ChEMBL
EP2 PE2R2 Mouse Prostanoid A pKi 5.23 5.23 5.23 ChEMBL
EP4 PE2R4 Mouse Prostanoid A pKi 5.64 5.64 5.64 ChEMBL
EP3 PE2R3 Mouse Prostanoid A pKi 6.96 6.96 6.96 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP3 PE2R3 Mouse Prostanoid A pIC50 6.24 6.24 6.24 ChEMBL