ANTAZOLINE


SMILES c1ccc(CN(CC2=NCCN2)c2ccccc2)cc1
InChIKey REYFJDPCWQRWAA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 265.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Guinea pig Histamine A pKd 7.14 7.14 7.14 ChEMBL
H1 HRH1 Rat Histamine A pKi 6.21 6.21 6.21 PDSP Ki database
H1 HRH1 Guinea pig Histamine A pKd 8.15 8.15 8.15 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
TA1 TAAR1 Human Trace amine A pEC50 5.37 5.37 5.37 ChEMBL
TSH TSHR Human Glycoprotein hormone A Potency 4.5 4.5 4.5 ChEMBL