CHEMBL609742


SMILES O=S(=O)(Nc1ccc2[nH]cc(C[C@H]3CCCN3)c2c1)c1ccccc1Cl
InChIKey CZEUYEVFOZRSCP-CQSZACIVSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 3
Rotatable bonds 5
Molecular weight (Da) 389.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1F 5HT1F Human 5-Hydroxytryptamine A pKi 7.91 7.91 7.91 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 7.06 7.06 7.06 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 8.52 8.52 8.52 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.25 6.25 6.25 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.26 6.26 6.26 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT6 5HT6R Human 5-Hydroxytryptamine A pEC50 8.89 8.89 8.89 ChEMBL