CHEMBL610261


SMILES Oc1ccc2c3c1O[C@H]1c4ncc(-c5ccc(Cl)cc5)cc4C[C@@]4(O)[C@@H](C2)N(CC2CC2)CC[C@]314
InChIKey WRVDUHKCIPYGNZ-FQYQUSJJSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 486.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Guinea pig Opioid A pKi 7.7 7.78 7.95 ChEMBL
μ OPRM Rat Opioid A pKi 7.29 7.29 7.29 ChEMBL
δ OPRD Human Opioid A pKi 8.66 9.2 9.74 ChEMBL
κ OPRK Human Opioid A pKi 7.7 7.7 7.7 ChEMBL
μ OPRM Human Opioid A pKi 7.29 7.29 7.29 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database