CHEMBL61819


SMILES COc1ccccc1N1CCN(CCCCc2ccc3c(c2)sc(=O)n3C)CC1
InChIKey IUIOIGDUPSHYOT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 411.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Bovine 5-Hydroxytryptamine A pIC50 6.0 6.0 6.0 ChEMBL
α1A ADA1A Bovine Adrenoceptors A pIC50 7.52 7.52 7.52 ChEMBL
D2 DRD2 Bovine Dopamine A pIC50 8.0 8.0 8.0 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pIC50 6.62 6.62 6.62 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pIC50 9.1 9.1 9.1 ChEMBL
5-HT1B 5HT1B Rat 5-Hydroxytryptamine A pIC50 6.52 6.52 6.52 ChEMBL