CHEMBL62601


SMILES COc1c(-c2nc(CNC[C@@H]3CCN(Cc4ccccc4)C3)co2)cc(Br)c2ccccc12
InChIKey DRRIHRQXXFYPBU-FQEVSTJZSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 505.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 4.0 4.0 4.0 ChEMBL
D4 DRD4 Human Dopamine A pKi 4.81 4.81 4.81 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.23 5.23 5.23 ChEMBL
D2 DRD2 Human Dopamine A pKi 4.34 4.55 4.76 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database