CHEMBL62602


SMILES COc1ccc(Br)cc1-c1nc(CNC[C@@H]2CCN(Cc3ccccc3)C2)co1
InChIKey HKAWCIGAEVMZGN-SFHVURJKSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 455.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 5.46 5.46 5.46 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.96 7.96 7.96 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.19 7.19 7.19 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.5 6.55 6.61 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database