NIFLUMIC ACID


SMILES O=C(O)c1cccnc1Nc1cccc(C(F)(F)F)c1
InChIKey JZFPYUNJRRFVQU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 282.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GPR35 GPR35 Human A orphans A pKi 5.44 5.44 5.44 ChEMBL
GPR35 GPR35 Human A orphans A pKi 8.26 8.26 8.26 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GPR35 GPR35 Human A orphans A pEC50 4.4 5.13 5.96 ChEMBL
GPR35 GPR35 Human A orphans A pIC50 5.89 5.89 5.89 ChEMBL