CHEMBL63329


SMILES Cc1ccc2c(c1)C(N1CCN(C)CC1)=Nc1cccnc1N2
InChIKey MMCMKWDIEUZMQB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 0
Molecular weight (Da) 307.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 7.68 7.68 7.68 ChEMBL
D1 DRD1 Rat Dopamine A pKi 6.4 6.4 6.4 ChEMBL
D2 DRD2 Rat Dopamine A pKi 6.28 6.28 6.28 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.44 7.44 7.44 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.23 5.23 5.23 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M1 ACM1 Rat Acetylcholine (muscarinic) A Potency 7.1 7.28 7.45 ChEMBL
NPS NPSR1 Human Neuropeptide S A Potency 4.9 4.9 4.9 ChEMBL