CHEMBL64288


SMILES COc1ccc(Br)cc1-c1nc(CN2CCN(c3ccccc3)CC2)co1
InChIKey TYIIYIRHCHVCLI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 427.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 6.43 6.43 6.43 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.18 6.18 6.18 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.16 6.32 6.48 ChEMBL
D1 DRD1 Bovine Dopamine A pKi 5.31 5.31 5.31 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database