CHEMBL70634


SMILES CS(=O)(=O)c1ccc(Cl)cc1NCC1=NCCN1
InChIKey VFLQPKLTPYIDEK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 287.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 5.53 5.53 5.53 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 5.62 5.62 5.62 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 5.32 5.32 5.32 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 6.27 6.27 6.27 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pEC50 7.21 7.21 7.21 ChEMBL
α2C ADA2C Human Adrenoceptors A pEC50 6.1 6.1 6.1 ChEMBL
α1A ADA1A Human Adrenoceptors A pEC50 8.55 8.55 8.55 ChEMBL