CHEMBL72850


SMILES CC1CN(C[C@H](Cc2ccccc2)C(=O)NCC(=O)O)CCC1(C)c1cccc(O)c1
InChIKey UPNUIXSCZBYVBB-PSWPWZSKSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 8
Molecular weight (Da) 424.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Mouse Opioid A pKd 8.7 8.7 8.7 ChEMBL
κ OPRK Guinea pig Opioid A pKd 7.8 7.8 7.8 ChEMBL
κ OPRK Guinea pig Opioid A pKi 7.4 7.4 7.4 ChEMBL
μ OPRM Rat Opioid A pKi 9.11 9.11 9.11 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database