CHEMBL74283


SMILES Brc1c(NC2=NCCN2)ccc2c1NCCN2
InChIKey CETMNKCDAHCKRC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 4
Rotatable bonds 1
Molecular weight (Da) 295.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 5.36 5.36 5.36 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 5.57 5.57 5.57 ChEMBL
α2B ADA2B Human Adrenoceptors A pKi 7.31 7.31 7.31 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 6.67 6.67 6.67 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 5.95 5.95 5.95 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 8.19 8.19 8.19 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pEC50 6.05 6.05 6.05 ChEMBL
α2C ADA2C Human Adrenoceptors A pEC50 6.98 6.98 6.98 ChEMBL
α2A ADA2A Human Adrenoceptors A pEC50 8.55 8.55 8.55 ChEMBL