CHEMBL78838


SMILES c1cncc(Cc2c[nH]cn2)c1
InChIKey IQMRECYOUIKYGG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 159.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pKi 6.16 6.58 7.0 ChEMBL
H3 HRH3 Human Histamine A pKi 7.12 7.2 7.28 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pEC50 4.82 4.82 4.82 ChEMBL
H3 HRH3 Human Histamine A pEC50 6.85 7.13 7.41 ChEMBL