CHEMBL80731


SMILES CCSc1cc2c(cc1F)CCN2C[C@H](C)N
InChIKey KAWSTPLVSKOAGD-VIFPVBQESA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 254.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.21 7.21 7.21 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 8.19 8.19 8.19 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.24 7.24 7.24 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pEC50 7.51 7.51 7.51 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 7.68 7.68 7.68 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pEC50 6.74 6.74 6.74 ChEMBL