PHENOTHIAZINE


SMILES c1ccc2c(c1)Nc1ccccc1S2
InChIKey WJFKNYWRSNBZNX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 0
Molecular weight (Da) 199.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.93 5.93 5.93 ChEMBL
A3 AA3R Human Adenosine A pKi 4.84 4.84 4.84 ChEMBL
CB1 CNR1 Human Cannabinoid A pKi 4.71 4.71 4.71 ChEMBL
D1 DRD1 Rat Dopamine A pKi 5.0 5.0 5.0 PDSP Ki database
D2 DRD2 Rat Dopamine A pKi 5.0 5.0 5.0 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pIC50 5.65 5.65 5.65 ChEMBL
A3 AA3R Human Adenosine A pIC50 4.59 4.59 4.59 ChEMBL
CB1 CNR1 Human Cannabinoid A pIC50 4.61 4.61 4.61 ChEMBL