CHEMBL130896


SMILES CCCCc1nc2ccc(NC(=O)NC3CCCCC3)cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1
InChIKey OLQFKFSAJNUOPT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 9
Molecular weight (Da) 524.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
AT1 AGTR1 Rabbit Angiotensin A pKi 7.54 7.54 7.54 ChEMBL
AT2 AGTR2 Human Angiotensin A pKi 6.32 6.32 6.32 ChEMBL
AT1 AGTR1 Human Angiotensin A pKi 7.54 7.54 7.54 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
AT1 AGTRB Rat Angiotensin A pIC50 7.58 7.58 7.58 ChEMBL