ArrestinDb

CHEMBL98241

SMILES	C[C@H](CN1CCN(c2cc(F)c(F)cc2F)CC1)N1C(=O)CC2(CCCC2)CC1=O
InChIKey	WCWNYVYNQAPOOX-OAHLLOKOSA-N

Chemical properties

Hydrogen bond acceptors	4
Hydrogen bond donors	0
Rotatable bonds	4
Molecular weight (Da)	423.2

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source
GTP No matches found	Uniprot No matches found	Species No matches found	Family No matches found	Class No matches found	Type No matches found	Min	Avg	Max	Database No matches found
5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pKi	6.31	6.41	6.52	ChEMBL
5-HT_1B	5HT1B	Human	5-Hydroxytryptamine	A	pKi	5.11	5.11	5.11	ChEMBL
5-HT_2C	5HT2C	Rat	5-Hydroxytryptamine	A	pKi	5.58	5.58	5.58	ChEMBL
D₂	DRD2	Rat	Dopamine	A	pKi	6.01	6.01	6.01	ChEMBL
D₂	DRD2	Human	Dopamine	A	pKi	6.24	6.24	6.24	ChEMBL
D₃	DRD3	Rat	Dopamine	A	pKi	6.92	6.92	6.92	ChEMBL
D₃	DRD3	Human	Dopamine	A	pKi	7.23	7.23	7.23	ChEMBL
D₄	DRD4	Human	Dopamine	A	pKi	7.31	7.31	7.31	ChEMBL
α_1A	ADA1A	Bovine	Adrenoceptors	A	pKi	5.23	5.23	5.23	ChEMBL
α_1A	ADA1A	Human	Adrenoceptors	A	pKi	4.83	5.69	6.54	ChEMBL
α_1B	ADA1B	Golden hamster	Adrenoceptors	A	pKi	6.77	6.77	6.77	ChEMBL
α_1B	ADA1B	Human	Adrenoceptors	A	pKi	6.72	6.76	6.78	ChEMBL
α_1D	ADA1D	Human	Adrenoceptors	A	pKi	8.8	8.86	8.89	ChEMBL

Showing 1 to 13 of 13 entries

Search:

Receptor					Activity				Source
GTP No matches found	Uniprot No matches found	Species No matches found	Family No matches found	Class No matches found	Type No matches found	Min	Avg	Max	Database No matches found
No data available in table

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