TETRAGASTRIN


SMILES CSCC[C@H](NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
InChIKey RGYLYUZOGHTBRF-BIHRQFPBSA-N

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Protein
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CCK2 GASR Rat Cholecystokinin A pKi 7.03 7.03 7.03 ChEMBL
CCK1 CCKAR Guinea pig Cholecystokinin A pKi 4.44 4.44 4.44 ChEMBL
CCK2 GASR Human Cholecystokinin A pKi 7.71 7.8 7.98 ChEMBL
CCK2 GASR Human Cholecystokinin A pKd 7.66 7.66 7.66 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CCK2 GASR Rat Cholecystokinin A pEC50 8.85 8.85 8.85 ChEMBL
CCK2 GASR Mouse Cholecystokinin A pIC50 8.61 8.61 8.61 ChEMBL
CCK1 CCKAR Rat Cholecystokinin A pIC50 5.37 5.37 5.37 ChEMBL