DPDPE


SMILES CC1(C)SSC(C)(C)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@H](Cc2ccccc2)C(=O)N[C@H]1C(=O)O
InChIKey MCMMCRYPQBNCPH-DVKRWUGUSA-N

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Protein
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Bovine Opioid A pKi 6.34 6.71 7.09 ChEMBL
μ OPRM Mouse Opioid A pKi 8.53 8.53 8.53 ChEMBL
δ OPRD Mouse Opioid A pKi 9.05 9.05 9.05 ChEMBL
μ OPRM Rat Opioid A pKi 5.55 5.94 6.21 ChEMBL
δ OPRD Human Opioid A pKi 8.4 8.7 9.3 ChEMBL
μ OPRM Human Opioid A pKi 6.3 6.3 6.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Mouse Opioid A pIC50 5.57 5.57 5.57 ChEMBL
δ OPRD Mouse Opioid A pIC50 6.21 8.33 8.8 ChEMBL
δ OPRD Mouse Opioid A pEC50 8.39 8.49 8.69 ChEMBL
κ OPRK Guinea pig Opioid A pIC50 8.68 8.68 8.68 ChEMBL
μ OPRM Rat Opioid A pIC50 5.43 6.11 6.42 ChEMBL
δ OPRD Human Opioid A pIC50 5.14 8.31 9.85 ChEMBL
δ OPRD Human Opioid A pEC50 7.8 8.68 9.85 ChEMBL
μ OPRM Human Opioid A pIC50 6.21 6.21 6.21 ChEMBL