KISS1-305


SMILES CNC(=N)NCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)NNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](Cc1ccncc1)NC(=O)[C@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
InChIKey YSVWFFNZZGLLAI-XNTOLAJGSA-N

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Na
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
kisspeptin KISSR Rat Kisspeptin A pKi 9.85 9.93 10.0 ChEMBL
kisspeptin KISSR Human Kisspeptin A pKi 9.96 10.02 10.05 ChEMBL
δ OPRD Human Opioid A pKi 7.32 7.32 7.32 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
kisspeptin KISSR Rat Kisspeptin A pEC50 8.0 8.88 9.77 ChEMBL
kisspeptin KISSR Human Kisspeptin A pEC50 8.59 9.08 9.57 ChEMBL
kisspeptin KISSR Human Kisspeptin A pIC50 8.05 8.05 8.05 ChEMBL