TP-040n


SMILES CN1CCN(c2ccnc(NCCc3ccccc3)n2)CC1
InChIKey BNXNWRSVYQHTOH-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Na
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT5A 5HT5A Human 5-Hydroxytryptamine A pKi 5.21 5.25 5.29 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 5.69 5.71 5.74 ChEMBL
H4 HRH4 Human Histamine A pKi 6.15 6.15 6.15 ChEMBL
α2B ADA2B Human Adrenoceptors A pKi 6.32 6.35 6.37 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 6.38 6.38 6.39 ChEMBL
H2 HRH2 Human Histamine A pKi 6.83 6.83 6.84 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.48 6.48 6.48 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.22 6.22 6.22 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.54 6.54 6.55 ChEMBL
H3 HRH3 Human Histamine A pKi 7.03 7.06 7.09 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.57 6.58 6.59 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.12 6.14 6.16 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database