TP-040


SMILES CC1CCN(c2ccnc(NCc3cn(C)cn3)n2)CC1
InChIKey PWKAYICUBVNJAZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Na
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 6.2 6.29 6.38 ChEMBL
α2B ADA2B Human Adrenoceptors A pKi 5.59 5.59 5.59 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 5.46 5.46 5.47 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.16 6.16 6.16 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.43 6.44 6.44 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database