CHEMBL499595


SMILES C[C@@H]1NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]2CCCN2C1=O
InChIKey OTUDCPUMJPNZRR-UYGLSEIWSA-N

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Protein
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Rat Opioid A pKi 8.51 8.51 8.51 ChEMBL
δ OPRD Mouse Opioid A pKi 5.08 5.08 5.08 ChEMBL
μ OPRM Rat Opioid A pKi 7.56 7.56 7.56 ChEMBL
κ OPRK Human Opioid A pKi 8.28 8.28 8.28 ChEMBL
μ OPRM Human Opioid A pKi 7.66 7.66 7.66 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Human Opioid A pIC50 8.3 8.7 9.09 ChEMBL
μ OPRM Human Opioid A pIC50 7.32 7.71 8.09 ChEMBL