CHEMBL131482


SMILES CC1SC2(CCCC2)C(=O)N1CCCCN1CCN(c2csc3cc(F)ccc23)CC1
InChIKey SYTKLFTVOOOLQR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 461.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 6.93 6.93 6.93 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.4 8.4 8.4 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pIC50 6.02 6.02 6.02 ChEMBL
D4 DRD4 Human Dopamine A pIC50 6.15 6.15 6.15 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pIC50 6.72 6.72 6.72 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pIC50 8.1 8.1 8.1 ChEMBL