CHEMBL506616


SMILES O=C1N[C@@H](Cc2ccccc2)C(=O)N2CCC[C@@H]2C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H]1Cc1c[nH]c2ccccc12
InChIKey GIZJWWQFOGQPRY-GCXHJFECSA-N

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Protein
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Rat Opioid A pKi 7.45 7.49 7.56 ChEMBL
δ OPRD Mouse Opioid A pKi 5.38 5.38 5.38 ChEMBL
μ OPRM Rat Opioid A pKi 6.21 6.26 6.35 ChEMBL
δ OPRD Human Opioid A pKi 5.7 5.7 5.7 ChEMBL
κ OPRK Human Opioid A pKi 7.5 7.52 7.54 ChEMBL
μ OPRM Human Opioid A pKi 6.89 6.89 6.9 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ A0A286XTF2 Guinea pig Opioid A pIC50 5.58 5.58 5.58 ChEMBL
κ OPRK Guinea pig Opioid A pIC50 7.33 7.33 7.33 ChEMBL
δ OPRD Human Opioid A pIC50 5.58 5.58 5.58 ChEMBL
κ OPRK Human Opioid A pIC50 6.36 6.85 7.33 ChEMBL
μ OPRM Human Opioid A pIC50 6.58 7.09 7.6 ChEMBL