CHEMBL5077293


SMILES COc1ccccc1-c1cc(C2CCNC2)ccc1Cl
InChIKey ALRBWNXPNRLJKC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Na
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1E 5HT1E Human 5-Hydroxytryptamine A pKi 6.11 6.11 6.11 ChEMBL
5-HT5A 5HT5A Human 5-Hydroxytryptamine A pKi 6.01 6.01 6.01 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 6.39 6.39 6.39 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 8.47 8.47 8.47 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.55 8.55 8.56 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.4 6.4 6.4 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.3 7.3 7.3 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.47 6.47 6.47 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.02 7.02 7.02 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pEC50 7.04 7.08 7.12 ChEMBL