CHEMBL5077561


SMILES CCC(=O)N(c1ccc(Cl)c(Cl)c1)C1CCN(C(=O)[C@H](Cc2ccc(Cl)cc2)NC(=O)[C@H]2Cc3ccccc3CN2C(=O)[C@@H](N)Cc2cc(C)c(O)c(C)c2)CC1
InChIKey SZGFKMMELMVQQF-VDYROPKHSA-N

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Na
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Rat Opioid A pKi 7.46 7.46 7.46 ChEMBL
δ OPRD Human Opioid A pKi 8.44 8.44 8.44 ChEMBL
κ OPRK Human Opioid A pKi 7.47 7.47 7.47 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Rat Opioid A pIC50 7.11 7.11 7.11 ChEMBL
δ OPRD Human Opioid A pIC50 8.11 8.11 8.11 ChEMBL
κ OPRK Human Opioid A pIC50 6.91 6.91 6.91 ChEMBL