CHEMBL5078669


SMILES CCC(=O)N(c1ccc(Cl)c(Cl)c1)C1CCN(C(=O)[C@H](Cc2ccc(Cl)cc2)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)CC1
InChIKey KDFZRMRUMBKVJQ-JDGSVOMQSA-N

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Na
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Rat Opioid A pKi 8.48 8.48 8.48 ChEMBL
δ OPRD Human Opioid A pKi 9.13 9.13 9.13 ChEMBL
κ OPRK Human Opioid A pKi 8.24 8.24 8.24 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Rat Opioid A pIC50 8.12 8.12 8.12 ChEMBL
δ OPRD Human Opioid A pIC50 8.8 8.8 8.8 ChEMBL
κ OPRK Human Opioid A pIC50 7.62 7.62 7.62 ChEMBL