CHEMBL5083183


SMILES CCC(=O)N(c1ccc(Cl)c(Cl)c1)C1CCN(C(=O)[C@H](Cc2ccccc2)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc2ccc(O)cc2)CC1
InChIKey OWUPLLATCGWWNP-MWOZDUBJSA-N

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Na
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Rat Opioid A pKi 8.19 8.19 8.19 ChEMBL
δ OPRD Human Opioid A pKi 8.68 8.68 8.68 ChEMBL
κ OPRK Human Opioid A pKi 7.36 7.36 7.36 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Rat Opioid A pIC50 7.83 7.83 7.83 ChEMBL
δ OPRD Human Opioid A pIC50 8.34 8.34 8.34 ChEMBL
κ OPRK Human Opioid A pIC50 6.74 6.74 6.74 ChEMBL