JNJ-63533054


SMILES O=C(N[C@H](c1ccccc1)C)CNC(=O)c1cccc(c1)Cl
InChIKey MWDVCHRYCKXEBY-LBPRGKRZSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 316.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Structure pdb 7VUG 7VUH 7VUJ 7VUI

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GPR139 GP139 Human A orphans A pKi 7.62 7.62 7.62 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GPR139 GP139 Human A orphans A pEC50 7.8 7.8 7.8 ChEMBL