JP1302


SMILES CN1CCN(CC1)c1ccc(cc1)Nc1c2ccccc2nc2c1cccc2
InChIKey QZKGUNQLVFEEBA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 368.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pKi 5.82 5.82 5.82 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 7.55 7.55 7.55 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 5.5 5.5 5.5 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2C ADA2C Human Adrenoceptors A pKB 6.9 7.35 7.8 Guide to Pharmacology