CHEMBL5091642


SMILES CCCC[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc1ccc(F)cc1)C(=O)N1CCC(N(C(=O)CC)c2ccc(Cl)c(Cl)c2)CC1
InChIKey UKUQNPULUQDCMS-XFQWPLCWSA-N

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Na
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Rat Opioid A pKi 8.47 8.47 8.47 ChEMBL
δ OPRD Human Opioid A pKi 9.24 9.24 9.24 ChEMBL
κ OPRK Human Opioid A pKi 7.7 7.7 7.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Rat Opioid A pIC50 8.09 8.09 8.09 ChEMBL
δ OPRD Human Opioid A pIC50 8.91 8.91 8.91 ChEMBL
κ OPRK Human Opioid A pIC50 7.08 7.08 7.08 ChEMBL