CLOFLUPEROL


SMILES C1CN(CCC1(C2=CC(=C(C=C2)Cl)C(F)(F)F)O)CCCC(=O)C3=CC=C(C=C3)F
InChIKey LZFSKNPPWIFMFL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 443.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.38 7.87 8.35 PDSP Ki database
D2 DRD2 Rat Dopamine A pKi 7.25 7.25 7.25 PDSP Ki database
D2 DRD2 Bovine Dopamine A pKi 9.3 9.3 9.3 PDSP Ki database
D1 DRD1 Bovine Dopamine A pKi 6.44 6.44 6.44 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database