DAMGO


SMILES CC(C(=O)NCC(=O)N(C)C(CC1=CC=CC=C1)C(=O)NCCO)NC(=O)C(CC2=CC=C(C=C2)O)N
InChIKey HPZJMUBDEAMBFI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 6
Rotatable bonds 13
Molecular weight (Da) 513.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Human Opioid A pKi 8.42 8.86 9.3 PDSP Ki database
δ OPRD Human Opioid A pKi 5.84 6.26 6.7 PDSP Ki database
κ OPRK Human Opioid A pKi 6.0 6.39 6.67 PDSP Ki database
κ OPRK Guinea pig Opioid A pKi 5.73 5.73 5.73 PDSP Ki database
δ A0A286XTF2 Guinea pig Opioid A pKi 6.74 6.74 6.74 PDSP Ki database
μ OPRM Rat Opioid A pKi 7.43 8.64 9.44 PDSP Ki database
μ OPRM Mouse Opioid A pKi 8.55 8.94 9.21 PDSP Ki database
δ OPRD Rat Opioid A pKi 7.07 7.1 7.12 PDSP Ki database
κ OPRK Rat Opioid A pKi 6.68 8.07 9.3 PDSP Ki database
CB1 CNR1 Human Cannabinoid A pKi 6.0 6.0 6.0 PDSP Ki database
A1 AA1R Human Adenosine A pKi 5.0 5.0 5.0 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database