PL017


SMILES CN(C(CC1=CC=CC=C1)C(=O)N2CCCC2C(=O)N)C(=O)C3CCCN3C(=O)C(CC4=CC=C(C=C4)O)N
InChIKey JAKBYSTWCHUQOK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 3
Rotatable bonds 9
Molecular weight (Da) 535.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Human Opioid A pKi 7.52 7.83 8.15 PDSP Ki database
δ OPRD Human Opioid A pKi 5.0 5.5 6.0 PDSP Ki database
κ OPRK Human Opioid A pKi 5.0 5.5 6.0 PDSP Ki database
κ OPRK Guinea pig Opioid A pKi 5.0 5.0 5.0 PDSP Ki database
δ A0A286XTF2 Guinea pig Opioid A pKi 5.0 5.0 5.0 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database