Methadone-HCL,(-)


SMILES CCC(=O)C(CC(C)N(C)C)(C1=CC=CC=C1)C2=CC=CC=C2.Cl
InChIKey FJQXCDYVZAHXNS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 345.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Human Opioid A pKi 8.84 9.03 9.22 PDSP Ki database
δ OPRD Human Opioid A pKi 6.0 6.44 6.88 PDSP Ki database
κ OPRK Human Opioid A pKi 6.49 6.49 6.49 PDSP Ki database
κ OPRK Guinea pig Opioid A pKi 6.14 6.14 6.14 PDSP Ki database
δ A0A286XTF2 Guinea pig Opioid A pKi 7.43 7.43 7.43 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database