NALTREXONE-HCl


SMILES C1CC1CN2CCC34C5C(=O)CCC3(C2CC6=C4C(=C(C=C6)O)O5)O.Cl
InChIKey RHBRMCOKKKZVRY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 377.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 6.83 7.4 7.97 PDSP Ki database
κ OPRK Human Opioid A pKi 8.41 8.91 9.4 PDSP Ki database
μ OPRM Human Opioid A pKi 8.82 9.17 9.7 PDSP Ki database
κ OPRK Guinea pig Opioid A pKi 9.22 9.22 9.22 PDSP Ki database
δ A0A286XTF2 Guinea pig Opioid A pKi 8.19 8.19 8.19 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database