ETORPHINE - HCI


SMILES CCCC(C)(C1CC23C=CC1(C4C25CCN(C3CC6=C5C(=C(C=C6)O)O4)C)OC)O.Cl
InChIKey JNHPUZURWFYYHW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 447.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Human Opioid A pKi 9.52 9.63 9.74 PDSP Ki database
δ OPRD Human Opioid A pKi 8.82 8.84 8.85 PDSP Ki database
κ OPRK Human Opioid A pKi 9.7 9.79 9.89 PDSP Ki database
κ OPRK Guinea pig Opioid A pKi 9.1 9.1 9.1 PDSP Ki database
δ A0A286XTF2 Guinea pig Opioid A pKi 9.15 9.15 9.15 PDSP Ki database
μ OPRM Rat Opioid A pKi 9.57 9.57 9.57 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database