NALORPHINE - HCI


SMILES C=CCN1CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)O)O[C@H]3[C@H](C=C4)O.Cl
InChIKey NAHATSPWSULUAA-ZQGPYOJVSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 347.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Human Opioid A pKi 8.18 8.7 9.01 PDSP Ki database
δ OPRD Human Opioid A pKi 6.83 7.09 7.35 PDSP Ki database
κ OPRK Human Opioid A pKi 8.96 9.03 9.1 PDSP Ki database
κ OPRK Guinea pig Opioid A pKi 8.77 8.77 8.77 PDSP Ki database
δ A0A286XTF2 Guinea pig Opioid A pKi 7.71 7.71 7.71 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database