WIN 44,441(-)


SMILES CC12CCN(C(C1(C)CCC(=O)CCC3CCCC3)CC4=C2C=C(C=C4)O)C
InChIKey LOYWOYCPSWPKFH-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 383.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Human Opioid A pKi 9.0 9.5 10.0 PDSP Ki database
δ OPRD Human Opioid A pKi 8.85 8.85 8.85 PDSP Ki database
κ OPRK Human Opioid A pKi 9.7 9.7 9.7 PDSP Ki database
κ OPRK Guinea pig Opioid A pKi 9.7 9.7 9.7 PDSP Ki database
δ A0A286XTF2 Guinea pig Opioid A pKi 9.05 9.05 9.05 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database